Applied Immunology - Lecture

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2024-2025

Tematika

Biotechnology is connected to immunology in several ways. The aim of this course is to introduce the biotechnology MSc students to this complex relationship. Understanding of the immunological steady state will serve as a starting point to interpret the pathological alterations of the immune system, for example hypersensitive reactions or immunodeficiencies. The importance of physiological- and pathological autoimmunity will be discussed. Immunological background of several biotechnology fields will be highlighted. Interaction between microbes and the immune system. Possibilities in immunomodulation and immunological therapies.

Előadások

• 1.

  Overview of the immune system: components, structure, functions. Immunological recognition.

  - Németh Péter János
• 2.

  Types of immune responses (elimination or tolerance).

  - Németh Péter János
• 3.

  Normal immune homeostasis and its potential disturbances.

  - Boldizsár Ferenc
• 4.

  Introduction to hypersensitive reactions.

  - Boldizsár Ferenc
• 5.

  Allergy (IgE-mediated hypersensitivity).

  - Berki Timea
• 6.

  Delayed type hypersensitivity.

  - Boldizsár Ferenc
• 7.

  Primary immunodeficiencies.

  - Balogh Péter
• 8.

  Secondary (acquired) immunodeficiencies, HIV, AIDS

  - Engelmann Péter András
• 9.

  From the humoral immune response to artificial antibody production (Hybridoma technique)

  - Németh Péter János
• 10.

  From the humoral immune response to artificial antibody production (Hybridoma technique)

  - Németh Péter János
• 17.

  Physiological and pathological mucosal immune responses-cells, processes and potential targets for restoration.

  - Kellermayer Zoltán
• 16.

  CAR T cells

  - Balogh Péter
• 19.

  Tolerance and autoimmunity

  - Németh Péter János
• 18.

  Tolerance and autoimmunity

  - Németh Péter János
• 20.

  Complex animal models of autoimmunity (RA)

  - Boldizsár Ferenc
• 21.

  Complex animal models of autoimmunity (SLE, Hemolytic anemia)

  - Boldizsár Ferenc
• 22.

  Complex animal models of innate immunity

  - Engelmann Péter András
• 11.

  Applications of monoclonal antibodies (medical diagnostics)

  - Berki Timea
• 12.

  Monoclonal antibodies for therapy

  - Berki Timea
• 13.

  Immunomodulation

  - Boldizsár Ferenc
• 14.

  Immunomodulation

  - Boldizsár Ferenc
• 15.

  Non-immune functions of lymphocytes-tissue regeneration. Ectopic and artificial lymphoid tissues.

  - Balogh Péter
• 23.

  Immune response against pathogens

  - Berki Timea
• 24.

  Immune response against pathogens

  - Berki Timea
• 25.

  Interactions between the microbiom and the immune system

  - Olasz Katalin Eszter
• 26.

  Interactions between the microbiom and the immune system

  - Olasz Katalin Eszter
• 27.

  Immune response against tumors

  - Németh Péter János
• 28.

  Immunological aspects of organ transplantation

  - Németh Péter János

Gyakorlatok

Szemináriumok

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Abul K. Abbas, Andrew H.H. Lichtman, Shiv Pillai: Cellular and MolecularImmunology, 10th edition, 2021.

Saját oktatási anyag

www.immbio.hu

Jegyzet

Lectures are available on www.immbio.hu.

Ajánlott irodalom

none

A félév elfogadásának feltételei

Reaching at least 50% on the midterm tests.

Félévközi ellenőrzések

Midterm tests will be conducted.

Távolmaradás pótlásának lehetőségei

none

Vizsgakérdések

Az előadások anyaga. www.immbio.hu

Vizsgáztatók

• Balogh Péter
• Berki Timea
• Boldizsár Ferenc
• Engelmann Péter András
• Németh Péter János

Gyakorlatok, szemináriumok oktatói